Arlene B Chapman Selected Research

Vasopressin Receptors (Arginine Vasopressin Receptor)

4/2021	The Effect of Tolvaptan on BP in Polycystic Kidney Disease: A Post Hoc Analysis of the TEMPO 3:4 Trial.
6/2020	The NOCTURNE Randomized Trial Comparing 2 Tolvaptan Formulations.
1/2019	Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease.
5/2017	Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial.
2/2017	Tolvaptan and Kidney Pain in Patients With Autosomal Dominant Polycystic Kidney Disease: Secondary Analysis From a Randomized Controlled Trial.
1/2016	Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial.
5/2011	Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 Study.
5/2007	Autosomal dominant polycystic kidney disease: time for a change?

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Arlene B Chapman Research Topics

Disease

65	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2022 - 01/2003
38	Hypertension (High Blood Pressure) 01/2022 - 03/2002
17	Essential Hypertension 01/2018 - 03/2002
16	Cysts 01/2020 - 09/2003
12	Chronic Kidney Failure (Chronic Renal Failure) 04/2021 - 05/2007
11	Disease Progression 04/2021 - 10/2011
8	Chronic Renal Insufficiency 01/2022 - 02/2014
8	Polycystic Kidney Diseases (Polycystic Kidney Disease) 04/2021 - 07/2008
6	Hypotension (Low Blood Pressure) 05/2018 - 03/2012
4	Renal Insufficiency (Renal Failure) 01/2022 - 12/2003
4	Pain (Aches) 01/2020 - 12/2012
4	Kidney Diseases (Kidney Disease) 01/2019 - 02/2017
4	Polycystic liver disease 11/2016 - 01/2003
3	Cardiovascular Diseases (Cardiovascular Disease) 04/2020 - 01/2010
3	Albuminuria 01/2019 - 10/2011
3	Hyperglycemia 01/2018 - 02/2014
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2015 - 01/2012
2	Body Weight (Weight, Body) 04/2021 - 01/2008
2	Nocturia 06/2020 - 01/2017
2	Coronary Artery Disease (Coronary Atherosclerosis) 11/2014 - 10/2012
2	IGA Glomerulonephritis (IGA Nephropathy) 11/2014 - 11/2012
2	Stroke (Strokes) 10/2012 - 01/2011
2	Myocardial Infarction 10/2012 - 01/2011
1	Nephrolithiasis 01/2022
1	Hyperuricemia 01/2021
1	Hereditary Nephritis (Alport Syndrome) 01/2021
1	Hypokalemia 01/2021
1	Chemical and Drug Induced Liver Injury 12/2020
1	Diarrhea 01/2020
1	Infections 01/2020
1	Constipation 01/2020
1	Hypoxia (Hypoxemia) 01/2018

Drug/Important Bio-Agent (IBA)

24	Antihypertensive Agents (Antihypertensives)IBA 01/2022 - 03/2002
24	Tolvaptan FDA Link 08/2021 - 05/2011
18	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 01/2021 - 03/2002
17	CreatinineIBA 01/2022 - 09/2003
16	Biomarkers (Surrogate Marker)IBA 04/2021 - 12/2003
15	TEMPOIBA 08/2021 - 05/2011
13	Pharmaceutical PreparationsIBA 01/2019 - 01/2008
10	Atenolol (Tenormin)FDA LinkGeneric 10/2016 - 01/2010
8	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 04/2021 - 05/2007
7	ReninIBA 11/2019 - 03/2002
7	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 01/2019 - 11/2002
7	Vasopressins (Vasopressin)IBA 01/2019 - 05/2011
6	AlbuminsIBA 01/2021 - 09/2003
6	Iothalamic Acid (Iotalamic Acid)FDA Link 12/2018 - 09/2003
5	Proteins (Proteins, Gene)FDA Link 04/2020 - 01/2007
5	Verapamil (Calan)FDA LinkGeneric 01/2018 - 01/2011
5	trandolapril (Mavik)FDA LinkGeneric 01/2018 - 01/2011
4	SodiumIBA 04/2021 - 03/2002
4	AngiotensinsIBA 05/2018 - 03/2012
4	AldosteroneIBA 06/2015 - 03/2002
4	Angiotensin Receptor AntagonistsIBA 01/2015 - 01/2008
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2015 - 10/2011
3	Fibroblast Growth Factor-23IBA 04/2021 - 09/2017
3	candesartanIBA 01/2019 - 01/2008
3	DiureticsIBA 01/2018 - 01/2008
3	Diltiazem (Cardizem)FDA LinkGeneric 01/2018 - 08/2013
3	1-dodecylpyridoxal (PLD)IBA 11/2016 - 01/2015
3	Glucose (Dextrose)FDA LinkGeneric 06/2015 - 01/2010
2	Losartan (Cozaar)FDA LinkGeneric 01/2022 - 01/2015
2	Metoprolol (Toprol-XL)FDA LinkGeneric 01/2022 - 12/2017
2	Chlorthalidone (Chlortalidone)FDA LinkGeneric 01/2021 - 12/2017
2	BilirubinIBA 12/2020 - 11/2017
2	Transaminases (Aminotransferases)IBA 11/2017 - 01/2016
2	Peptides (Polypeptides)IBA 01/2017 - 01/2013
2	Telmisartan (Micardis)FDA Link 12/2014 - 12/2014
2	Lisinopril (Prinivil)FDA LinkGeneric 12/2014 - 12/2014
2	Indicators and Reagents (Reagents)IBA 01/2014 - 07/2013
2	HDL LipoproteinsIBA 01/2013 - 01/2010
2	ElectrolytesIBA 12/2012 - 09/2003
2	HDL CholesterolIBA 01/2012 - 03/2011
2	GadoliniumIBA 02/2010 - 04/2009
2	Uric Acid (Urate)IBA 01/2010 - 01/2007
1	Cystatin CIBA 01/2022
1	Carvedilol (Coreg)FDA LinkGeneric 01/2022
1	Natriuretic AgentsIBA 04/2021
1	PotassiumIBA 01/2021
1	bardoxolone methylIBA 01/2021
1	TabletsIBA 06/2020
1	TRPP Cation ChannelsIBA 04/2020
1	Dopamine D5 ReceptorsIBA 01/2020
1	Sorting NexinsIBA 01/2020
1	2,5- dibromo- 2- (beta- naphthyl)indan- 1,3- dioneIBA 01/2020
1	Erythropoietin FDA Link 12/2019
1	CalcineurinIBA 11/2019
1	Inositol PhosphatesIBA 11/2019
1	Caffeine (No Doz)FDA LinkGeneric 12/2018
1	Protein Kinases (Protein Kinase)IBA 01/2018
1	ThiazidesIBA 01/2018
1	Chlorothiazide FDA LinkGeneric 01/2018
1	Angiopoietin-2IBA 01/2018
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 06/2017

Therapy/Procedure

17	Therapeutics 01/2020 - 12/2003
4	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020 - 01/2015
2	Transplantation 01/2022 - 01/2016
2	Treatment Delay 01/2018 - 01/2017
1	Polypharmacy 01/2022
1	Ambulatory Care (Outpatient Care) 01/2019
1	Precision Medicine 12/2017